Elaboration of a biocompatible surface/Evaluation of respiratory and immune toxicity

Your needs

• Confer novel functionalities on a surface  
• Change the surface energy
• Increase the sensitivity of a biosensor
• Measure the effects of your substances in a liquid or solid phase on the xenobiotic metabolism of living organisms
• Study the early toxicological effects in vitro  
• Assess a toxicological file
• Validate the effects of synthetic or natural molecules on a biological target
• Develop a physical sensor that responds to a biological stimulus

Our solutions

• Modify the surface according to the desired property
• Graft molecules or biomolecules to increase the sensitivity of a sensor
• Increase the non-stick properties of surfaces  
• Set-up a study protocol on an appropriate cell-line
• Identify the best strategy to evaluate a biological or toxicity effect through the selection of key endpoints
• Choose the best physical, physicochemical and biological strategies to design a prototype sensor (transversal skills)

Keywords

• Functional surface
• Surface property
• Nanoparticles
• Artificial fibre
• Polymer
• Intelligent material
• Biomaterial
• Toxicology in vitro
• Cell biology
• Marker of biological effects
• Toxicological expertise
• Molecular biology

Related skills

• Surface characterization
• Polymers modification  
• Polymers characterization
• Design of microfluidic systems  
• Structural and microstructural characterizations

Contacts

• Contact the research group:
  bertrand.rihn@univ-lorraine.fr
  +33 (0) 3 72 74 26 95
   
• Contact the Technology Transfer Office (TTO):
  ijl-tto@univ-lorraine.fr
  +33 (0) 3 72 74 26 04